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One of the gene clusters contains two huge open reading frames, together encoding 12 modules of nonribosomal peptide synthetases (NRPS).
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Gene disruption of one of the NRPS led to the disappearance of a metabolite produced in the wild type and the elimination of its antibacterial activity.
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The metabolite and antibacterial activity were also affected by the disruption of some of the flanking genes.
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